Specialized High-Capacity Mitochondria Fuel Cell Invasion
Discovery of specialized high-capacity mitochondria that localize to the invasion site and produce elevated ATP to power cell invasion.
Publications
The Actin Protrusion Deforms the Nucleus During Invasion Through Basement Membrane
Study of how actin protrusions mechanically deform the nucleus to facilitate basement membrane penetration.
The Caenorhabditis elegans LON-1 Protein Requires Its CAP Domain for Function in Regulating Body Size and BMP Signaling
Investigation of the CAP domain’s role in LON-1 function, sterol binding, and regulation of body size and BMP signaling.
The β Integrin Modulates Serotonin Sensitivity via NPxY Motifs to Regulate Egg Laying and Mechanosensation Behaviors in Caenorhabditis elegans
Investigation of how β integrin NPxY phosphorylation modulates neurotransmitter response and sensory behaviors.
An Integrin Binding Motif in TLN-1/Talin Plays a Minor Role in Motility and Ovulation
Analysis of the integrin binding motif in TLN-1/talin and its limited impact on motility and ovulation.
The RGD (Arg-Gly-Asp) is a Potential Cell-Binding Motif of UNC-52/PERLECAN
Investigation of the RGD motif in UNC-52/perlecan as an essential integrin-binding ligand.
Mutations in the Cell-Binding Motif of lam-3/Laminin α Reveal Hypercontraction Behavior and Defective Sensitivity to Levamisole in Caenorhabditis elegans
Characterization of the RGD motif in lam-3/laminin α and its role in motility regulation in C. elegans.